General features
| Gene ID | MYPE6860
|
| Type | CDS
|
| From | 883159
|
| To | 882695
|
| Strand | -
|
| General name | dhfR
|
| Definition | dihyrofolate reductase
|
| nt length | 465
|
| aa length | 154
|
| m.w. | 18274.69
|
| COG | [H] Coenzyme metabolism
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| mpne | MPN300 dyr dihydrofolate reductase 353535:355055 | 102 | 5.3e-28
|
| mgen | WP_009885765.1 dihydrofolate reductase [Mycoplasma genitalium] | 90 | 1.0e-25
|
| mpul | WP_041364161.1 dihydrofolate reductase [Mycoplasma pulmonis] | 106 | 1.1e-31
|
| mmob | WP_011264555.1 dihydrofolate reductase [Mycoplasma mobile] | 87 | 4.2e-24
|
| mgal | WP_011113649.1 segregation/condensation protein A [Mycoplasma gallisepticum] | 120 | 4.3e-34
|
| uure | WP_012560310.1 dihydrofolate reductase [Ureaplasma urealyticum] | 112 | 5.1e-34
|
| phyt | WP_011160668.1 MULTISPECIES: dihydrofolate reductase [Candidatus Phytoplasma asteris] | 73 | 5.2e-19
|
| bsub | NP_390064.1 dihydrofolate reductase [Bacillus subtilis subsp. subtilis str. 168] | 87 | 1.1e-23
|
| cace | WP_010966286.1 MULTISPECIES: dihydrofolate reductase [Clostridium] | 93 | 4.8e-26
|
| ecoli | NP_414590.1 dihydrofolate reductase [Escherichia coli str. K-12 substr. MG1655] | 84 | 1.6e-22
|
*mpne, Mycoplasma pneumoniae; mgen, Mycoplasma genitalium; mpul, Mycoplasma pulmonis; mmob, Mycoplasma mobile; mgal, Mycoplasma gallisepticum; uure, Ureaplasma urealyticum; phyt, ; bsub, Bacillus subtilis; cace, Clostridium acetobutylicum; ecoli, Escherichia coli K-12;
Pfam search result:
| Model | No. | Descrip
tion | Position (aa) | Score | E-value
|
| DHFR_1 | 1 | Dihydrofolate reductase | 2-145 | 142.7 | 8e-42
|
BLAST search result (top 10 hits)

| ID Description | Identity | Score | E-value
|
| ref|WP_011077508.1| dihydrofolate reductase [Mycoplasma penetrans] | 154/154 (100%) | 796 | 3.6e-107
|
| ref|WP_004025489.1| dihydrofolate reductase [Mycoplasma iowae] | 72/133 (54%) | 326 | 1.1e-35
|
| ref|WP_119569040.1| dihydrofolate reductase [Inordinaticella fortuita] | 75/154 (48%) | 316 | 4.7e-34
|
| ref|WP_053392836.1| dihydrofolate reductase [Leptotrichia sp. oral taxon 212] | 74/153 (48%) | 303 | 4.9e-32
|
| ref|WP_095544688.1| dihydrofolate reductase [Candidatus Izimaplasma sp. ZiA1] | 68/154 (44%) | 299 | 1.4e-31
|
| ref|WP_013386940.1| dihydrofolate reductase [Ilyobacter polytropus] | 65/153 (42%) | 296 | 4.3e-31
|
| ref|WP_163654046.1| dihydrofolate reductase [Listeria sp. PSOL-1] | 53/125 (42%) | 295 | 8.6e-31
|
| ref|WP_052663072.1| segregation/condensation protein A [Mycoplasma pirum] | 61/153 (39%) | 312 | 1.8e-30
|
| ref|WP_003748519.1| dihydrofolate reductase [Listeria seeligeri] | 61/153 (39%) | 287 | 1.1e-29
|
| ref|WP_010619785.1| dihydrofolate reductase [Lactobacillus malefermentans] | 53/142 (37%) | 287 | 1.2e-29
|
Maintained by Jun Ishikawa