General features
| Gene ID | MYPE4140
|
| Type | CDS
|
| From | 545803
|
| To | 547926
|
| Strand | +
|
| General name | topA
|
| Definition | DNA topoisomerase I
|
| nt length | 2124
|
| aa length | 707
|
| m.w. | 81232.34
|
| COG | [L] Replication, recombination and repair
|
Orthologs (if any)
| Bacteria* | Reciprocally best hit to | Score | E-value
|
| mpne | MPN261 topA DNA topoisomerase I 312256:314391 | 655 | 0.0e+00
|
| mgen | WP_009885678.1 type I DNA topoisomerase [Mycoplasma genitalium] | 627 | 0.0e+00
|
| mpul | WP_041364416.1 type I DNA topoisomerase [Mycoplasma pulmonis] | 364 | 8.6e-119
|
| mmob | WP_011264602.1 type I DNA topoisomerase [Mycoplasma mobile] | 357 | 3.2e-116
|
| mmyc | NP_975898.1 DNA topoisomerase I [Mycoplasma mycoides subsp. mycoides SC str. PG1] | 277 | 3.9e-85
|
| mgal | WP_011113893.1 type I DNA topoisomerase [Mycoplasma gallisepticum] | 620 | 0.0e+00
|
| uure | WP_012560269.1 type I DNA topoisomerase [Ureaplasma urealyticum] | 540 | 0.0e+00
|
| phyt | WP_011160653.1 type I DNA topoisomerase [Onion yellows phytoplasma] | 419 | 8.9e-140
|
| bsub | NP_389494.1 DNA topoisomerase I [Bacillus subtilis subsp. subtilis str. 168] | 478 | 5.2e-161
|
| cace | WP_010965091.1 MULTISPECIES: type I DNA topoisomerase [Clostridium] | 439 | 7.3e-146
|
| ecoli | NP_415790.1 DNA topoisomerase 1 [Escherichia coli str. K-12 substr. MG1655] | 353 | 2.4e-111
|
*mpne, Mycoplasma pneumoniae; mgen, Mycoplasma genitalium; mpul, Mycoplasma pulmonis; mmob, Mycoplasma mobile; mmyc, Mycoplasma mycoides; mgal, Mycoplasma gallisepticum; uure, Ureaplasma urealyticum; phyt, ; bsub, Bacillus subtilis; cace, Clostridium acetobutylicum; ecoli, Escherichia coli K-12;
Pfam search result:
| Model | No. | Descrip
tion | Position (aa) | Score | E-value
|
| Topoisom_bac | 1 | DNA topoisomerase | 137-565 | 386.9 | 1.2e-115
|
| Toprim | 1 | Toprim domain | 4-122 | 100.4 | 5.7e-29
|
| zf-C4_Topoisom | 2 | Topoisomerase DNA binding C4 zinc finger | 592-631, 637-673 | 93.4 | 4.8e-27
|
| Toprim_4 | 1 | Toprim domain | 65-117 | 27.3 | 3.8e-06
|
BLAST search result (top 10 hits)
| ID Description | Identity | Score | E-value
|
| ref|WP_011077240.1| type I DNA topoisomerase [Mycoplasma penetrans] | 707/707 (100%) | 3756 | 0.0e+00
|
| ref|WP_129374388.1| type I DNA topoisomerase [Mycoplasma penetrans] | 706/707 (99%) | 3746 | 0.0e+00
|
| ref|WP_004024942.1| type I DNA topoisomerase [Mycoplasma iowae] | 465/697 (66%) | 2450 | 0.0e+00
|
| ref|WP_036452389.1| type I DNA topoisomerase [Mycoplasma iowae] | 464/697 (66%) | 2445 | 0.0e+00
|
| ref|WP_129692644.1| type I DNA topoisomerase [Mycoplasma iowae] | 464/697 (66%) | 2442 | 0.0e+00
|
| ref|WP_052663495.1| type I DNA topoisomerase [Mycoplasma testudinis] | 373/671 (55%) | 1995 | 0.0e+00
|
| ref|WP_052663066.1| type I DNA topoisomerase [Mycoplasma pirum] | 365/668 (54%) | 1929 | 0.0e+00
|
| ref|WP_033160278.1| type I DNA topoisomerase [Mycoplasma alvi] | 358/668 (53%) | 1875 | 0.0e+00
|
| ref|WP_017532806.1| type I DNA topoisomerase [Mycoplasma pneumoniae] | 352/669 (52%) | 1692 | 0.0e+00
|
| ref|WP_053344037.1| type I DNA topoisomerase [Mycoplasma pneumoniae] | 351/669 (52%) | 1692 | 0.0e+00
|
Maintained by Jun Ishikawa