General features

Gene IDMYPE8250
TypeCDS
From1105471
To1104359
Strand-
General nametrmD
DefinitiontRNA-(5-methylaminomethyl-2-thiouridylate) methyltransferase
nt length1113
aa length370
m.w.42410.03
COG[J] Translation, ribosomal structure and biogenesis


Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
mpneMPN422 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 509863:5087513223.5e-110
mgenWP_162465265.1 tRNA 2-thiouridine(34) synthase MnmA [Mycoplasma genitalium]2941.9e-99
mpulWP_010925359.1 tRNA 2-thiouridine(34) synthase MnmA [Mycoplasma pulmonis]3101.4e-105
mmobWP_156768871.1 tRNA 2-thiouridine(34) synthase MnmA [Mycoplasma mobile]2992.9e-101
mmycNP_975433.1 tRNA-specific 2-thiouridylase MnmA [Mycoplasma mycoides subsp. mycoides SC str. PG1]3499.4e-121
mgalWP_011113349.1 tRNA 2-thiouridine(34) synthase MnmA [Mycoplasma gallisepticum]3062.4e-100
uureWP_004026155.1 tRNA 2-thiouridine(34) synthase MnmA [Ureaplasma urealyticum]3627.1e-126
phytWP_011160500.1 tRNA 2-thiouridine(34) synthase MnmA [Onion yellows phytoplasma]2691.5e-89
bsubNP_390627.3 tRNA-specific 2-thiouridylase [Bacillus subtilis subsp. subtilis str. 168]2805.8e-93
caceWP_010965531.1 MULTISPECIES: tRNA 2-thiouridine(34) synthase MnmA [Clostridium]2047.8e-64
ecoliNP_415651.4 tRNA-specific 2-thiouridylase [Escherichia coli str. K-12 substr. MG1655]3078.9e-104

*mpne, Mycoplasma pneumoniae; mgen, Mycoplasma genitalium; mpul, Mycoplasma pulmonis; mmob, Mycoplasma mobile; mmyc, Mycoplasma mycoides; mgal, Mycoplasma gallisepticum; uure, Ureaplasma urealyticum; phyt, ; bsub, Bacillus subtilis; cace, Clostridium acetobutylicum; ecoli, Escherichia coli K-12;

Pfam search result:



ModelNo.Descrip tionPosition (aa)ScoreE-value

tRNA_Me_trans1tRNA methyl transferase2-364428.61.5e-128

NAD_synthase1NAD synthase2-9132.93.5e-08

ThiI1Thiamine biosynthesis protein (ThiI)3-4727.91.5e-06

BLAST search result (top 10 hits)

ID DescriptionIdentityScoreE-value
ref|WP_011077646.1| tRNA 2-thiouridine(34) synthase MnmA [Mycoplasma penetrans]370/370 (100%)19570.0e+00
ref|WP_004024877.1| tRNA 2-thiouridine(34) synthase MnmA [Mycoplasma iowae]199/363 (54%)10271.9e-135
ref|WP_038102516.1| tRNA 2-thiouridine(34) synthase MnmA [Ureaplasma diversum]193/365 (52%)9612.5e-125
ref|WP_070406665.1| MULTISPECIES: tRNA 2-thiouridine(34) synthase MnmA [unclassified Spiro...195/366 (53%)9343.3e-121
ref|WP_127093155.1| tRNA 2-thiouridine(34) synthase MnmA [Spiroplasma poulsonii]196/366 (53%)9326.1e-121
ref|WP_004026155.1| tRNA 2-thiouridine(34) synthase MnmA [Ureaplasma urealyticum]188/363 (51%)9301.7e-120
ref|WP_162649593.1| tRNA 2-thiouridine(34) synthase MnmA [Spiroplasma sp. TIUS-1]196/364 (53%)9282.2e-120
ref|WP_040093328.1| tRNA 2-thiouridine(34) synthase MnmA [Spiroplasma poulsonii]195/366 (53%)9282.4e-120
ref|WP_129620067.1| tRNA 2-thiouridine(34) synthase MnmA [Mycoplasma gallinaceum]188/364 (51%)9231.3e-119
ref|WP_126821235.1| tRNA 2-thiouridine(34) synthase MnmA [Spiroplasma endosymbiont of Mega...193/366 (52%)9222.2e-119


Maintained by Jun Ishikawa