General features

Gene IDMYPE6860
TypeCDS
From883159
To882695
Strand-
General namedhfR
Definitiondihyrofolate reductase
nt length465
aa length154
m.w.18274.69
COG[H] Coenzyme metabolism


Orthologs (if any)

Bacteria*Reciprocally best hit toScoreE-value
mpneMPN300 dyr dihydrofolate reductase 353535:3550551025.3e-28
mgenWP_009885765.1 dihydrofolate reductase [Mycoplasma genitalium]901.0e-25
mpulWP_041364161.1 dihydrofolate reductase [Mycoplasma pulmonis]1061.1e-31
mmobWP_011264555.1 dihydrofolate reductase [Mycoplasma mobile]874.2e-24
mgalWP_011113649.1 segregation/condensation protein A [Mycoplasma gallisepticum]1204.3e-34
uureWP_012560310.1 dihydrofolate reductase [Ureaplasma urealyticum]1125.1e-34
phytWP_011160668.1 MULTISPECIES: dihydrofolate reductase [Candidatus Phytoplasma asteris]735.2e-19
bsubNP_390064.1 dihydrofolate reductase [Bacillus subtilis subsp. subtilis str. 168]871.1e-23
caceWP_010966286.1 MULTISPECIES: dihydrofolate reductase [Clostridium]934.8e-26
ecoliNP_414590.1 dihydrofolate reductase [Escherichia coli str. K-12 substr. MG1655]841.6e-22

*mpne, Mycoplasma pneumoniae; mgen, Mycoplasma genitalium; mpul, Mycoplasma pulmonis; mmob, Mycoplasma mobile; mgal, Mycoplasma gallisepticum; uure, Ureaplasma urealyticum; phyt, ; bsub, Bacillus subtilis; cace, Clostridium acetobutylicum; ecoli, Escherichia coli K-12;

Pfam search result:



ModelNo.Descrip tionPosition (aa)ScoreE-value

DHFR_11Dihydrofolate reductase2-145142.78e-42

BLAST search result (top 10 hits)

ID DescriptionIdentityScoreE-value
ref|WP_011077508.1| dihydrofolate reductase [Mycoplasma penetrans]154/154 (100%)7963.6e-107
ref|WP_004025489.1| dihydrofolate reductase [Mycoplasma iowae]72/133 (54%)3261.1e-35
ref|WP_119569040.1| dihydrofolate reductase [Inordinaticella fortuita]75/154 (48%)3164.7e-34
ref|WP_053392836.1| dihydrofolate reductase [Leptotrichia sp. oral taxon 212]74/153 (48%)3034.9e-32
ref|WP_095544688.1| dihydrofolate reductase [Candidatus Izimaplasma sp. ZiA1]68/154 (44%)2991.4e-31
ref|WP_013386940.1| dihydrofolate reductase [Ilyobacter polytropus]65/153 (42%)2964.3e-31
ref|WP_163654046.1| dihydrofolate reductase [Listeria sp. PSOL-1]53/125 (42%)2958.6e-31
ref|WP_052663072.1| segregation/condensation protein A [Mycoplasma pirum]61/153 (39%)3121.8e-30
ref|WP_003748519.1| dihydrofolate reductase [Listeria seeligeri]61/153 (39%)2871.1e-29
ref|WP_010619785.1| dihydrofolate reductase [Lactobacillus malefermentans]53/142 (37%)2871.2e-29


Maintained by Jun Ishikawa