Translation, ribosomal structure and biogenesis  Transcription  Replication, recombination and repair
 Cell cycle control, cell division, chromosome partitioning  Posttranslational modification, protein turnover, chaperones  Cell wall/membrane/envelope biogenesis
 Cell motility  Inorganic ion transport and metabolism  Signal transduction mechanisms
 Energy production and conversion  Carbohydrate transport and metabolism  Amino acid transport and metabolism
 Nucleotide transport and metabolism  Coenzyme metabolism  Lipid metabolism
 Secondary metabolites biosynthesis, transport and catabolism  General function prediction only  Function unknown
 not in COGs  Stable RNA